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Assistance programs for EYLEA® (aflibercept) injection cost Assistance programs for EYLEA® (aflibercept) injection cost

Assistance Programs

There are assistance options available for eligible patients without commercial insurance to help with the cost of EYLEA. Whether you have government-issued insurance—such as Medicare—no insurance, or your insurance doesn’t cover EYLEA, we may be able to help.


Whether you have Medicare or other insurance through a government healthcare program and need help with out-of-pocket costs for EYLEA, we may be able to assist.

If you suffer from Wet Age-related Macular Degeneration (Wet AMD), Diabetic Macular Edema (DME), Diabetic Retinopathy (DR), or Macular Edema following Retinal Vein Occlusion (MEfRVO), EYLEA4U can connect you with patient assistance through an independent charitable foundation.

Your live EYLEA4U Support Specialist will:

  • Let you know the different foundation options
    (Call 1-855-EYLEA4U (1-855-395-3248) and press Option 4 Monday through Friday 9 AM to 8 PM Eastern Time for assistance.)
  • Refer you to a foundation of your choice
  • Provide you all the information to help you apply
  • Follow up with you until a decision is made on your application

*Regeneron does not influence or control the operations of these independent charitable foundations and cannot guarantee assistance will be provided.

Alternate coverage referral for anti-VEGF treatment

Patient Assistance Program

If you are uninsured or find yourself without coverage for EYLEA, the Patient Assistance Program (PAP) can provide eligible patients with EYLEA free of charge. To qualify, you must:

  • Be uninsured or lack coverage for EYLEA
  • Live in the United States or its territories or possessions
  • Show financial need (based on total annual household adjusted gross income*)

*You will need to provide financial documentation to support this information.

Get EYLEA at no cost with the Patient Assistance Program.
EYLEA4U® will assist with getting your prescription.


Once EYLEA4U receives your application, your Support Specialist will:

  1. Verify that you meet the program requirements
  2. Send a confirmation letter about your enrollment to your doctor’s office upon approval
  3. Make sure that your EYLEA gets shipped to your doctor’s office

EYLEA4U offers live support

EYLEA4U Support Specialists are here to listen to your story and answer your questions. These Specialists can help by:

  • Determining the support program that may be right for you
  • Providing information about your health plan
  • Working with your doctor’s office and health plan to help determine your coverage

Receive support by calling an EYLEA4U® Support Specialist at 1-855-EYLEA4U (1-855-395-3248) Monday through Friday 9 AM to 8 PM Eastern Time. Press 2 for Medical Information questions, 3 to report an adverse event, 4 for patient assistance programs, or 6 if you need help getting to and from your eye appointments.

EYLEA4U® Support Specialists are available via phone.



Helpful resources for people living with low vision and their caregivers.

Get tips for living with low vision, what to talk with your doctor about, how to approach appointments/treatment, and more.

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  • EYLEA® (aflibercept) Injection is a prescription medicine administered by injection into the eye. You should not use EYLEA if you have an infection in or around the eye, eye pain or redness, or known allergies to any of the ingredients in EYLEA, including aflibercept.
  • Injection into the eye with EYLEA can result in an infection in the eye and retinal detachment (separation of retina from back of the eye). Inflammation in the eye has been reported with the use of EYLEA.
  • In some patients, injections with EYLEA may cause a temporary increase in eye pressure within 1 hour of the injection. Sustained increases in eye pressure have been reported with repeated injections, and your doctor may monitor this after each injection.
  • There is a potential risk of serious and sometimes fatal side effects related to blood clots, leading to heart attack or stroke in patients receiving EYLEA.
  • Serious side effects related to the injection procedure with EYLEA are rare but can occur including infection inside the eye and retinal detachment.
  • The most common side effects reported in patients receiving EYLEA are increased redness in the eye, eye pain, cataract, vitreous (gel-like substance) detachment, vitreous floaters, moving spots in the field of vision, and increased pressure in the eye.
  • It is important that you contact your doctor right away if you think you might be experiencing any side effects, including eye pain or redness, light sensitivity, or blurring of vision, after an injection.
  • EYLEA is for prescription use only. For additional safety information, please talk to your doctor and see the full Prescribing Information for EYLEA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit, or call 1-800-FDA-1088.


EYLEA® (aflibercept) Injection 2 mg (0.05mL) is a prescription medicine approved for the treatment of patients with Wet Age-related Macular Degeneration (AMD), Macular Edema following Retinal Vein Occlusion (RVO), Diabetic Macular Edema (DME), and Diabetic Retinopathy (DR).

Please see the full Prescribing Information for EYLEA.

The information contained herein is provided for general educational purposes. If you have any questions, talk to your doctor.

For U.S. Residents Only

EYLEA AND EYLEA4U are registered trademarks of Regeneron Pharmaceuticals, Inc.

© 2020, Regeneron Pharmaceuticals, Inc. All rights reserved.
777 Old Saw Mill River Road,
Tarrytown, NY 10591

EYL.19.10.0149 EYL.19.10.0149


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